I am on a laptop at home all the time. I usually remove the battery door, and blow out any dust visible. then i blow into the air exit holes forcing any dust back ut the way it came in.There are also access doors for ram and other components that i remove and clean.
Then i put the small rould brush adaptor on my vacuum, and suck up any dust through the fan inlet.
I find the keys on the keypad, are closer together than a regular keyboard, and mine doesnt accumulate a lot of dust.
I clean the screen with flat screen cleaner, never soap and water.