I don't use Outlook Express so I'm not sure how to help you. But once you hopefully get sorted out, do the following to avoid spam:
1. Never, never, did I say never?, reply to spam. All that does is confirm that your email address is valid, which means it will stay on spammer lists.
2. Create a freebie email account online (Gmail, Hotmail, Yahoo, AOL, it doesn't matter) and use that to register for websites, enter online contests, etc. One way spammers get email addresses is to pick them up in public access areas, so you want to avoid using the one you have at work or at home.
3. Never post your home or work email address here or in other public forums. Use PMs or the email function via the board.
300+ spam a day, geez that would really bug me... hope you get it sorted out.
Mike