I envy you, I was in Tofino 5 weeks ago and the drive there from the mainland is INCREDIBLE!!! Leave in the morning if you can, and plan on the whole day to get there. Make sure that you stop in the Macmillan Blodel forest to be BLOWN AWAY by the trees. For fishing, there are charters out of the main harbour, however you may want to go to the hotsprings as well.
The one thing to remember is BC does not stand for British Columbia, but rather Bring Cash!