My short answer is yes, but most of the time I don't think it does. The guys above are right, it depends on many factors. I usually carry around 2 rods with me, one with lighter mono, and one with heavy braid. I use braid 99% of the time, but if its not working I switch to mono. Most of the time this switch makes no difference at all.
To me its not so much how you fish, but where.