The regulatory approval is new.
“mRNA vaccines have been tested in humans before, for at least four infectious diseases: rabies, influenza, cytomegalovirus, and Zika.”
source and mRNA described:
https://www.medpagetoday.com/infectiousdisease/covid19/89998
As for non-mRNA, “Currently, there are five vaccines in development for Covid-19 with intranasal routes of administration with spike protein in the formulation.”
They have not had clinical trials in humans yet, or hadn’t at the time of the article below.
source: https://www.sciencedaily.com/releases/2020/08/200821155747.htm
They offered the following hopeful observations in the animal trials: “In contrast, the nasal delivery route prevented infection in both the upper and lower respiratory tract -- the nose and lungs -- suggesting that vaccinated individuals would not spread the virus or develop infections elsewhere in the body.”