In clear water, I think using a fluoro leader does make an important difference, particularly if you are using braid. I used to put on fluoro leaders just for pike, but became a convert for other applications while fishing for smallies up north last year. With Power Pro on in a clear shield lake, the line could be seen from the Moon, and I couldn't coax any smallies to hit the lure for days literally. Once I tied on about six feet of fluoro, the fish began to hit like there was no tomorrow.
Of course, it could all have been just a fluke, but the confidence alone was enough to make me a believer. Give it a try and see if you like it; if not, you can always go back to mono.