Well, I'm certainly no expert but I KNOW one thing. The next genuine world record muskie will be caught in Canada. There are only a handful of spots on the map that can harbour that kind of a beast. Here's my short list in no particular order.
St-Lawrence River (this is one of the bodies of water where Americans have a chance at it.)
Ottawa River
Georgian Bay
Lake St Clair
Niagara....not sure...
Lake of the Woods ( another shot for an American record)
There are a couple of others...maybe.
Nipissing is a possibility...Lake Ontario, I don't think so.